No reason not to, it lets everything start to settle in and you can get a cycle going. When it comes time to plant, just draw the water down to make it easier and you'll be fine. I would however avoid keeping the lights on for extended periods of time
if adding water, dechlorinate 24 hours before adding the SafeStart.
I filled my 50 gallon yesterday and dechlorinated.
I dumped in SafeStart about an hour before heading to the LFS today. Bought 6 angels and so far they are happy as clams. I got a nitrite rise after about 4 hours so they are working.
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