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Try to make/shape your mesh bag to fit well into, and cover as much of the cavity of the filter you're placing it into. I have found the best success by having the thickness level of purigen in the bag about 1/4" to 1/2", to allow water flow to penetrate through the Purigen particulates as much as possible for best effectiveness.
Also, be sure the bag is very fine mesh, otherwise you'll have Purigen all over your tank.
I find it nevessary to double bag to prevent dispersal of the Purigen.
 
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