I also am of the mindset from experience to also take the "do not disturb" suggestion with a grain of salt.
I have a 30 gallon low-tech planted aquarium with Seachem Flourite substrate that I started just about 1 year ago. I started off with not disturbing the substrate but to tell you the truth, especially with several varieties of Gouramis, Cherry Barbs, Otos, Corydora mates, it is better to vacuum clean the substrate gently weekly. In time, keeping the water chemistry in a good range that meets the needs of the inhabitants and also adding several ferts at regular periods, I can say the ecosystem is doing better and the plants are thriving. I have Taiwan Moss, Aniubias, Crypts, and Java Ferns that are doing well and the fish are all getting along well.
Unexpected "chemistry" may begin to build up on the bottom if you simple never vacuum the bottom substrate in an enclosed aquarium. True, in nature, there is no vacuuming going on weekly but then again nature provides an abundance of dynamic widespread systems of rivers, streams, lakes, etc. etc that are in motion.
You can wait a bit in the beginning, but in time, begin gently vacuuming the substrate on a regular schedule. If you use root tabs, take note where you place them to avoid pulling up the nutrients.
Just food for thought