I've built a wet/dry for a reef tank out a acyrlic, made a few pre-filters, other small things. It all gets down to craftsmanship like any project. Straight cuts, tight clamping prior to using the Weld-On. I prefer to use Lexan when I can. i love the stuff If it's strong enough to use for bullet proof windows, there won't be much it can't handle for us. I recently built a batter tray for my Scion XB out of 3/8" Lexan.
There a guy selling it on ebay from Indiana. Great seller, I've bought several sheets from him. He'll even makes a few cuts for free. He also sells Weld-On but that has to ship on it's own as it't Haz-Mat rated. I alway buy an extra needle dropper, I can bever sems to find those things in my shop area.