This sounds like it will be a very nice project. The problems I can see are as follows. You may have some trouble keeping CO2 levels high enough throughout the whole tank. I would recommend having at least two entry points with CO2 enriched water. I know Aqua Medic rates their reactor (I use one myself) for 500 gallons, or whatever, but you still may have trouble keeping CO2 enriched water in areas far from the filter return. Also, you are talking about a LOT of light. While plants like a lot of light, at some point you start having other issues like algae battles, excessive pruning, extreme fert dosing, heat, evaporation, etc. Even if you somehow managed to avoid those issues (you won't), you have a lot less room for error with such high lighting. As oblongshrimp mentioned, I would definitely consider 150 watt HQI instead of 250. I hope you can post some pictures as things progress! Best of luck.
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