Acrylic vs Glass... I can move a 50 gal glass tank pretty easily. Much bigger than 50 gals and a glass tank is too big to muscle around by myself. I had a 110G tall tank with 1/2" glass and it was a bear to move even with help. If I ever did a big tank again I think I would go acrylic, for a 50 gal I think I would just stick with glass.
A friend has a "Glass Cages" aquarium and she is very pleased with the company.