should work pretty well...
i'd suggest not running the co2 into the venturi, but directly into the lowest point in the chamber so the bubbles will fight to float up against the current, and shrink along the way... this provides the most efficient diffusion rates.
as a bonus with having the venturi, you can attach it to the top of the chamber where gas collects in pockets, allowing them to be sucked back into the power head, chopped up, and more easily pushed out of the reactor (this is mostly O2 and not CO2, and should be eliminated from the reactor to increase it's efficiency) many people eliminate the gas pocket with a "release valve" which is just an airline or valve connected in the same position that can be opened to allow the o2 to escape into the air. (kind of a reverse venturi... doesn't necessarily work on the venturi principle, but it uses an airline to remove air from the chamber instead of put it in)
with a flow rate at 600gph, you'll blow all of your gas straight out of the reactor and into the tank without diffusing it, unless this unit is much larger than i'm picturing in my head... a flow rate of 200-300 gph is probably still on the high side for most applications, but people with canisters at this flow rate are able to diffuse CO2 very effectively.
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