Erythromycin - The Planted Tank Forum
 
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post #1 of 12 (permalink) Old 07-04-2015, 12:47 AM Thread Starter
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Erythromycin

I am planning to use Erythromycin to kill off BGA.

Is this safe with shrimps?
And can I use this while still dosing my seachem ferts?
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post #2 of 12 (permalink) Old 07-04-2015, 01:29 AM
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OK with ferts. I do not know about shrimp.
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post #3 of 12 (permalink) Old 07-04-2015, 01:39 AM
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I just used it in a 10g tank @ 1/2 strength as directed for BGA and it didn't hurt the
ghost shrimp I have in there.

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post #4 of 12 (permalink) Old 07-04-2015, 02:09 AM Thread Starter
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I have RCS and Amanos, anyone have experience with these?
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post #5 of 12 (permalink) Old 07-04-2015, 02:23 AM
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Quote:
Originally Posted by Kdog View Post
I have RCS and Amanos, anyone have experience with these?

I just finished dosing the recommended full strength and my Fire RCS & Amanos took no notice. Actually they seem to be more active now. BGA is gone.

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post #6 of 12 (permalink) Old 07-04-2015, 05:35 AM Thread Starter
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The instruction on the API Erythromycin says dose 4 times, do you guys really dose that many times?
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post #7 of 12 (permalink) Old 07-04-2015, 01:37 PM
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Quote:
Originally Posted by Kdog View Post
The instruction on the API Erythromycin says dose 4 times, do you guys really dose that many times?
E.M. Erythromycin is an antibiotic used in this application to kill BGA (BGA is actually a bacteria, not algae). As with any antibiotic, you should follow through with all doses. If not there may be a spot or two not treated and the bacteria will grow right back.

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post #8 of 12 (permalink) Old 07-04-2015, 08:48 PM Thread Starter
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I just finished dosing the recommended full strength and my Fire RCS & Amanos took no notice. Actually they seem to be more active now. BGA is gone.
I noticed that you said you've used the med. at full strength,
for API E.M. Erythromycin it is 1 packet per 10g. You don't think it will be too strong. The others on this forum all said to use half dose.
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post #9 of 12 (permalink) Old 07-04-2015, 09:20 PM
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Quote:
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I noticed that you said you've used the med. at full strength,
for API E.M. Erythromycin it is 1 packet per 10g. You don't think it will be too strong. The others on this forum all said to use half dose.

I don't pretend to be a marine biologist of any sort, therefore I followed directions to the letter (including the water changes). I used one packet per 10 gallons for 2 doses (24 hours apart), performed a 25% water change, then repeated it for the 2nd round of 2 doses.

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post #10 of 12 (permalink) Old 07-04-2015, 09:23 PM
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I ended a terrible two-month-long BGA outbreak with erythromycin. I dosed as instructed for 5 days and did a blackout as well. Afterwards I did a water change and removed as much visible BGA as possible. The BGA is completely gone now (though I think the ammonia spike may have led to a bit of spirogyra...).

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post #11 of 12 (permalink) Old 07-06-2015, 12:07 AM
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It is actually unfortunate that API suggests that 4 dose regimen. This is probably done in analogy to the use in Human medicine. For example, Azithromycin (an Erythromycin derivative) comes in a 5 pill blister pack (1 pill each day) to make sure that an effective dose is delivered to ALL body tissue, especially the lung. Since the antibiotic has to be transported to the tissue by the blood, this 5-day regiment is required to ascertain that all infectious bacteria are killed.

In the aquarium, however, an easier regiment can be used as this environment is very different. Normally, the water is circulated to allow gases and fertilizers to be distributed quickly. This also aids greatly in the distribution of any medicine.

Since cyanobacteria are not invasive, their treatment with Erythromycin is actually quite effective. As cyanobacteria grow mostly on surfaces (plants, substrate) and some also in the water column, the antibiotic Erythromycin can penetrate these blue-green bacteria quickly and kill them within a day.

It is recommended to use between 200 to 250 mg of Erythromycin for 10 gallons. It is imperative that this dose is used. When using antibiotics it is a must to use the maximum dose first (different from chemical reagents). Often LFS people suggest to use low amounts. Don't do half a dose, that's the wrong approach! When using the maximum amount of antibiotic, treatment of the aquarium infection with a single dose is sufficient. (Of course, multiple dosing can be used, but that is really not necessary).
Erythromycin at the recommended max. dose is a very safe antibiotic.
(It works by binding selectively to the 50S subunit of the bacterial ribosome and thus inhibits translation of bacterial mRNA that ultimately leads to cell death.) As only certain bacteria have this ribosome, Erythromycin has no effect on fish, plants, shrimp, or snails.
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post #12 of 12 (permalink) Old 07-07-2015, 07:09 PM Thread Starter
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Thanks for the information!
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