Let's throw out some rough numbers. I'm dosing 5N and 1P in each macro dose, and my accumulation is 30N and 6P. Say I change 50%, so my next doses would go up like this: 20/4, 25/5, 30/6.
If I front load, I basically maintain 30/6 all the time because the 50% being replaced is immediately brought back up to levels that were in the tank.
I have been front loading 2/3 up front, 2 days of micros, last macro, 2 days of micros. Not really convinced any of it matters or makes a difference honestly.