I did this just recently. I think the most important thing I did was go slow and watch my fish. I had everything come in on a Friday and planned to set everything up Saturday. Saturday morning I attached the regulator to the tank, attached the CO2 line to the diffuser, and installed the diffuser inline. I attached the solenoid to the timer and waited. Prior to everything coming on I adjusted the working pressure and tank valve as directed. When the solenoid came on with the lights I adjusted the needle valve to some ridiculously small amount and waited a few hours. I mean, this was ridiculous. Probably 5 bubbles in ten seconds. I later increased it. The next day I again waited until everything came on and started the process of increasing the amount of CO2 again. I've now landed at about 2 bps but have gone up to 3 with no ill effects to the fish. For me, though, the drop checker changes at this amount of CO2 and that's good enough for me. No need to push it to the limit.
Go slow, watch your fish, and, if you have a bubble counter, watch that as well. There's also a relationship between CO2, PH, and KH, but I don't know enough to tell you more about it. There's plenty of threads both here and through a google search that can help you with that. Some people purchase a PH monitor to help with this. I did not.