Magnesium Sulfate (Epsom Salt)
Reducing the number of burden organisms by saline purges is an alternative method in the treatment of parasitic infestation, especially from luminal parasites. Saline purges all act in a similar mechanism by which the anions and cations are slowly absorbed from the digestive tract.
Magnesium salts frequently used as saline purgatives are Magnesium Sulfate, (Epsom salts), Magnesium Hydroxide, Magnesium Oxide, (milk of magnesia), and Magnesium Citrate, (Jenkins, 1988). They retain or attract water into the intestinal lumen mainly by osmosis, which distends the gut and increases peristalsis, thus producing defecation. Another mode of action of magnesium salts is causing the release of cholecystokinin, which increases peristaltic activity of the intestine (Jenkins, 1988); intraluminal parasites then will be expelled from host. The concentration of saline purgatives should be isotonic such as 6% solution of Epsom salt to get a quick purgative action (Alexander, 1985). In the present study, magnesium sulfate which may be helpful in reducing the number of diplomonads was examined for an efficacy in inhibiting the parasite’s growth.
excerpt from here:
much more reliable than peas.