I have moved smaller reef tanks with sand beds that I did not want to disturb more times than I want to think about (nothing bigger than 20 gallon) .
One thing I have learned was very helpful if you want to keep the substrate intact for the move, is to have a piece of plywood next to the tank. Once you get it drained, two people transfer the tank to the plywood, and then you carry the tank by holding the plywood. Do not let it slide off of course!!!
Wet substrate is VERY heavy, and it is easy to twist and torque the tank when trying to carry it, putting it on a board that has a larger footprint in the tank reduces stress on the glass seams.