I think the angels would be fine, and no grow-out tank would be necessary.
As they get large the Oto cats could be at risk; angels have been known to eat small fish that will fit into their mouths. IMO the rest of the fish should be fine, though.
(I also read a report in TFH of an angel having to have an oto cat cut out of its mouth b/c the oto's spines got wedged when the angel tried to eat it. Probably not very likely but it has happened?)
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