How big are you? I'm not a collector, but I view this as pretty simple. Different guns for different situations. You really can't go wrong with a Mossberg or Remington 870 12 gauge. You can't go wrong with a Ruger 10/22 takedown. Can't go wrong with a high quality AR (most expensive), or a high quality .308. From there you can go into specialized weapons (AR pistol, 30-06) These are just my opinions. Personally I also like 9mm's (for the wife) and .45 ACP. I only purchase Glock pistols though.
I am 5'11 and around 220lbs.