It depends on what you what to do.
I have a low tech tank with aquarium gravel and dose excel. Plants do grow. But not all of them. I have, over time, added some of the Schultz Pond substrate to give a little extra boost when plants started to do very poorly.
Now I can't imgaine you would want to do gravel with a high light Co2 tank, but I don't know much about that
EHEIM 2213 #317