That is actually what I have in my 75 gallon. The tank and substrate I got second hand from another TPT member, so the amazonia is a few years old. I really don't have much for plants yet, but the person I got the tank from had absolutely beautiful growth with it. The plants I do have in the tank have really nice roots established so far, and I got 2-3 lbs. of unused amazonia which I put some of it into my nano tank mixed with fluval stratum. I dont even touch that tank, and it's low light but the plants are very healthy. It seems in my 75 that I have more eco-complete on top, and I do get a certain amount of cloudiness from the amazonia anytime I mess with the tank, but that clears up in a few days. Hope I helped.