Thanks. Having it operate constantly at an angle might be a little difficult because it would throw off the orientation of the manifold, but I could certainly tip it at a steep angle during initial startup and waterchanges to help clear out any bubbles that build up.
I'm going to be using a 2" PVC tube for the heater portion. I anticipate that the large diameter tube should help to prevent bubbles from causing a problem. I'm also going to be pushing a good deal of flow through this thing (pressure rated pump putting out 850gph @ 0' head) so that should also help to force out bubbles.
Any thoughts about whether it would be ok for this to sit on the bottom of the stand? The plumbing would really fit together best that way.